Sunday, October 25, 2009

IRIS Summary for 1,2,3-trichloropropane

BrooklynDodger(s) comment: The Dodger(s) figure this is a drinking water contaminant. As with most IRIS chemicals, the chronic RfC is essentially zero. This came to attention because other bloggers noted OMB meddling. OMB was selling site specificity, animal to man, which is an old Houdini chestnut.

Critical Effect
Point of Departure*
Chronic RfC
peribronchial lymphoid hyperplasia in male rats

13-week inhalation Study

Johannsen et al., 1988
BMC10: 1.6 ppm
BMCL10: 0.84 ppm
BMCLADJ: 0.90 mg/m3
BMCLHEC: 0.90 mg/m3
0.0003 mg/m3

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