IRIS Summary for 1,2,3-trichloropropane

BrooklynDodger(s) comment: The Dodger(s) figure this is a drinking water contaminant. As with most IRIS chemicals, the chronic RfC is essentially zero. This came to attention because other bloggers noted OMB meddling. OMB was selling site specificity, animal to man, which is an old Houdini chestnut.


http://www.epa.gov/iris/subst/0200.htm

Critical Effect	Point of Departure*	UF	Chronic RfC
peribronchial lymphoid hyperplasia in male rats 13-week inhalation Study Johannsen et al., 1988	BMC10: 1.6 ppm BMCL10: 0.84 ppm BMCLADJ: 0.90 mg/m3 BMCLHEC: 0.90 mg/m3	3000	0.0003 mg/m3